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Tuesday, December 20, 2011
Pet meds to Help a Dog with Degenerative Joint Disease (Arthritis)
Wednesday, December 14, 2011
LowBackSpinalDecompressionBackPainVideo
Tuesday, December 13, 2011
Bone Marrow-Derived Progenitors (Handbook of Experimental Pharmacology)
!±8± Bone Marrow-Derived Progenitors (Handbook of Experimental Pharmacology)
The ambitious goal of this volume is to provide – in chapters written by accomplished scientists and experts in their field – a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. With excitement generated almost daily about the possible uses of stem cells to treat human disease, but the controversy surrounding their use still raging, adult bone-marrow derived cells are more readily available, and have a staggering range of uses.
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Tuesday, November 15, 2011
How Does Degenerative Disc Disease Lead to Spinal Arthritis?
As one ages, the spinal intervertebral disc undergoes significant changes. Normally the intervertebral disk is comprised of 80% water. With age, that percentage begins to decrease and the spinal disc begins to lose hydration and undergo degeneration.
Some discs undergo rapid degeneration and that can lead to degenerative disc disease. This may or may not lead to pain. The disc can lose height from lack of water, and it can also start to bulge similar to a tire that is getting flat and bulging. Disc degeneration is diagnosed from either x-rays or an MRI, which can be ordered by a Pain Management Doctor.
Just because a person has degeneration present of spinal discs does not mean pain is inevitable as there are many individuals walking around with discs that are dehydrating, degenerating, and bulging but not causing any pain at all.
As the spinal disc continues to degenerate, it can lead to a cascade of degenerative spinal arthritis that occurs as follows. As the disc loses water and degenerates, it loses disc height. The joints behind the disc space, called facet joints, begin to experience abnormal stresses as the disc becomes defective in its ability to absorb stresses. These stresses go to the rest of the spinal elements at the affected level, in this case the facet joints.
The facet joints begin to degenerate and become arthritic, this involves overgrowth of bone around the joint and further pain. Because the degenerative disc is not always affected symmetrically, the patient may end up with scoliosis due to the degeneration that continues to build on itself.
Treatments for degenerative disc disease are multiple. They are all quality of life treatments, as degenerative disc disease and spinal arthritis are not life threatening. Pain management doctors offer facet injections, nucleoplasty, physical therapy, spinal decompression therapy, bracing, radiofrequency ablation, among other treatments. Surgery should be considered as an absolute last resort.
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Sunday, October 23, 2011
Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and Protocols (Methods in Molecular Biology)
!±8± Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and Protocols (Methods in Molecular Biology)
Embryonic stem cells (ESCs) offer an unlimited self-renewing capacity, as opposed to the limits of adult stem cells; therefore, ESCs represent an almost bottomless resource for regenerative medicine and tissue engineering approaches. In Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and Protocols, accomplished investigators provide detailed descriptions on how to expand ESCs from the most commonly used species ex vivo, i.e. mouse and human, in static culture as well as in controllable bioreactor processes. The thorough and timely volume summarizes the methods that may be used to differentiate these cells along the desired lineage of choice, be it osteoblasts, osteoclasts, or chondrocytes, and consequentially also offers analysis tools for the characterization of resulting cells and evaluation of differentiation effectiveness. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls. Dependable and cutting-edge, Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and Protocols supplies the tools necessary to allow researchers to carry out critical research needed in order to bring this burgeoning and vitally important field closer to the clinic and to ensure the widespread application of a successful strategy.
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Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and Protocols (Methods in Molecular Biology)
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